Presence of quinolone resistance to qnrB1 genes and blaOXA-48 carbapenemase in clinical isolates of Klebsiella pneumoniae in Spain.

نویسندگان

  • J M Rodríguez Martínez
  • P Díaz-de Alba
  • Lopez-Cerero
  • G Ruiz-Carrascoso
  • R Gomez-Gil
  • A Pascual
چکیده

A study is presented on the presence of quinolone resistance qnrB1 genes in clinical isolates belonging to the largest series of infections caused by OXA-48-producing Klebsiella pneumoniae in a single-centre outbreak in Spain. Evidence is also provided, according to in vitro results, that there is a possibility of co-transfer of plasmid harbouring blaOXA-48 with an other plasmid harbouring qnrB1 in presence of low antibiotic concentrations of fluoroquinolones, showing the risk of multi-resistance screening.

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عنوان ژورنال:
  • Enfermedades infecciosas y microbiologia clinica

دوره 32 7  شماره 

صفحات  -

تاریخ انتشار 2014